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BenU Faculty since 2014
Postdoctoral Fellow: Vanderbilt University, Jeffrey Johnston (2012-2014)
Ph.D. Chemistry, Colorado State University, Tomislav Rovis (2012)
B.S. Chemistry, Calvin College, Ronald Blakespoor (2006)
Organic Chemistry and Organic Chemistry Laboratory
Asymmetric organocatalysis, reaction development, synthesis of biologically important molecules including potential malaria and cancer therapeutics, green chemistry, chemical education
Current Research Projects:
My research program focuses on developing new and environmentally friendly chiral organocatalysts and ligands to create sustainable routes to cancer and malaria therapeutics.
Current and Former Research Students:
Cameron Pombert (Biochemistry)
Mike Strongy (Chemistry)
Mohammed Farhan (Business with Science Applications)
Rubush, D. M. * 2014. Diphenylphosphoric Acid. e-EROS Encyclopedia of Reagents for Organic Synthesis. 1–6.
Colorado State University
"Stereoselective Synthesis of Dioxolanes and Oxazolidines via a Desymmetrization Acetalization/Michael Cascade." David M. Rubush and Tomislav Rovis* Synlett 2014, 25, 713-717.
"An Asymmetric Synthesis of 1,2,4-Trioxane Anticancer Agents via Desymmetrization of Peroxyquinols through a Brønsted Acid Catalysis Cascade." Journal of the American Chemical Society David M. Rubush, Michelle A. Morges, Barbara J. Rose, Douglas H. Thamm, and Tomislav Rovis* 2012, 134, 13554-13557.
"Photochemical Synthesis of 3-Alkynals from 1-Alkynoxy-9,10-anthraquinones." Ronald L. Blankespoor*, Peter J. Boldenow, Eric C. Hansen, Jeffrey M. Kallemeyn, Andrew G. Lohse, David M. Rubush and Derek Vrieze Journal of Organic Chemistry 2009, 74, 3933-3935.
Member, American Chemical Society, Organic Division
Peer-Reviewed and Invited Presentations:
“Enantioselective Chiral Acid-Catalyzed Desymmetrization of p-Quinols and p-Peroxyquinols to form Heterocycles” Rubush, D. M.; Rovis, T. 242th American Chemical Society National Meeting, Denver, CO; August 2011. (Talk)
“Progress Toward the Total Synthesis of Stemocurtisine Utilizing an Asymmetric Stetter Reaction” Rubush, D. M.; Rovis, T. 240th American Chemical Society National Meeting, Boston, MA; August 2010. (Talk)
“Toward the Total Synthesis of Stemocurtisine Utilizing an Asymmetric Intramolecular Stetter Reaction” Rubush, D. M.; Rovis, T. National Organic Chemistry Symposium, Boulder, CO; June 2009. (Poster)
“Progress Toward the Total Synthesis of Stemocurtisine” Rubush, D. M.; Rovis, T. Albert I. Meyers Symposium, Fort Collins, CO; October 2008. (Poster)
“Synthesis of Beta-Alkynals via the Photolysis of Substituted Anthraquinones” Blankespoor, R. L.; Boldenow, P. J.; Lohse, A. G.; Rubush, D. M. 235th American Chemical Society National Meeting, New Orleans, LA; April 2008. (Poster)